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This methyl group is trans to the other methyl groups. One notable characteristic of these steroids is that they make the steroid much more difficult for the liver to degrade and process into waste products and these steroids usually have a longer half life than their non-alkylated counterparts, is clenbuterol safe for females. This is because the methyl prevents the steroid from fitting into the active site on the various liver enzymes that process steroids. One example of a 17 alpha alkylated steroid is Oxandrolone, shown above. Note the CH3 on C17.
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